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Six pathways that decide how you feel
Compound lists are useless without the biology underneath them. Each hub explains one pathway, then links both the peptides and the practices that act on it — because in almost every case, the practice has the better evidence.
Mitochondria & mental energy
Why depression tracks with impaired cellular energy production, and what mitochondrial peptides, nutrition and sleep actually do about it.
6 compounds on this pathway →BDNF & neuroplasticity
How BDNF-raising peptides open a plasticity window — and why what you do during that window determines whether anything changes.
5 compounds on this pathway →Dopamine & drive
What dopamine actually governs, why anhedonia is a motivation problem rather than a pleasure problem, and where peptides and practice fit.
2 compounds on this pathway →Nerve regeneration
Peripheral nerves regenerate at roughly a millimetre a day. The central nervous system largely does not. What that means for peptides and practice.
6 compounds on this pathway →Inflammation & mood
Why inflammatory markers are elevated in a subset of depression, what causes it, and which peptides and practices act on the pathway.
6 compounds on this pathway →HPA axis & stress
How chronic stress dysregulates cortisol rhythm, what that does to mood and sleep, and the peptides and practices that act on it.
3 compounds on this pathway →